Every morning feels like a tightrope walk.
You guide your child through breakfast. You coax them into their clothes. Sometimes, they’re calm. Other times, a meltdown explodes without warning.
I know this dance well. My daughter, Mei, 8 years old, was diagnosed with autism and ADHD. We love her fiercely—but the challenges? They’re heartbreaking.
Speech therapy, sensory breaks, mindfulness apps, schedule charts… we tried it all. And yet, some mornings, Mei still seemed lost in worry or overwhelm.
Then, a friend suggested something new: PS128. A probiotic she’d read about in science journals. “It might help with mood and focus,” she said softly.
Cue skepticism. Another supplement?
But as we dove in, I discovered something gentle, promising—and worth sharing with you, mom to mom.
PS128 stands for Lactiplantibacillus plantarum PS128—a specific strain of probiotic discovered in Taiwanese fermented vegetables.
But let’s skip the bio jargon. PS128 is a psychobiotic: a friendly gut bacterium that can gently support mood, behavior, and cognitive clarity.
It’s not a medicine. It’s not a cure. Think of it as a tiny helper in your child’s gut, working alongside therapies and routines you already trust.
One of the strongest pieces of evidence comes from a 2019 randomized, double-blind, placebo-controlled trial in Taiwan involving boys ages 7–15 with autism spectrum disorder.
In just four weeks of PS128, these children showed:
Less defiance and oppositional behavior
Better attention, especially in younger kids
Reductions in anxiety and rule-breaking
This wasn’t a small survey—it was a rigorous clinical trial showing real improvements in behavior.
A real-world Italian study (Mensi et al., 2021) involved 131 autistic children and adolescents who took PS128 or other probiotics.
Results?
Children taking PS128 showed greater behavioral improvement
Fewer side effects compared to other probiotics
Notably stronger benefits in younger children
This study echoed clinical trials, underscoring that PS128 isn’t just lab theory—it’s working in real families. You can read the details here.
What if a probiotic and hormone therapy worked even better together?
In a 2021 MDPI trial, autistic children took PS128 alongside oxytocin over 28 weeks.
Results showed significant improvements in:
Social responsiveness
Behavior checklists
Overall clinical impressions
This suggests PS128 might enhance traditional therapies—a hopeful option for families exploring combined approaches.
Kids with Tourette’s often have ADHD too. A 2021 PS128 clinical trial involving children with Tourette’s syndrome showed:
No change in tics
But significant improvements in ADHD symptoms—especially attention and impulse control
That’s important for our neurodivergent children who fight double battles. PS128 may help both, even if it’s not treating the tic itself.
Picture your child’s gut as their home base.
If the floors are messy (bad bacteria), the brain’s signals get jumbled. PS128 helps tidy things:
Promotes friendly gut bacteria
Reduces gut inflammation
Boosts mood molecules like serotonin and dopamine
In short: a happier gut can help a calmer child—even on stressful days.
We used PS128 alongside:
Occupational therapy
Speech support
Predictable routines
Outdoor time and movement breaks
Simple diet (whole foods + healthy fats)
By 2 weeks: Mei slept more deeply.
By 4 weeks: we saw fewer classroom outbursts.
By 8 weeks: books and boards felt easier. Change. It happened.
Izzy (Teen, Autism):
“New shoes. No tears. For the first time ever.”
Mom says PS128 helped her adjust to change. Read Izzy’s story here
Another mom:
“It’s cut my son’s anxiety in half.”
A heartfelt note from a Facebook parent group.
These stories mimic my own. Small shifts. Quiet celebrations.
Licensed as Neuralli MP, containing 60 billion CFU PS128
GRAS (Generally Recognized as Safe) certified
No serious side effects in trials involving kids aged 5–18
We started with ½ capsule, mixing with yogurt or milk
Increased to a full capsule after two weeks
Always consult your pediatrician if child is on other meds
Is it safe for toddlers?
Studies include children as young as 5. Your pediatrician can advise on younger ones.
How soon results appear?
Trials saw behavioral improvements in just 4 weeks; many moms report changes around 8 weeks.
Is it a cure?
No. It helps with mood, attention, behavior—not autism or ADHD as diagnoses.
What if there’s no improvement?
Withdraw after 8–12 weeks. It’s gentle and doesn’t harm.
Our care plan included:
Routine (predictable schedule)
Therapy (OT, speech, counseling)
Nutrition (whole grains, veggies, healthy fats)
Exercise (daily movement)
Emotional tools (mindfulness, breathing apps)
PS128 (as a gut-brain ally)
This multimodal approach allowed us to celebrate every small win—and they add up.
Liu et al., 2019 – 4-week RCT trial in autistic boys aged 7–15 showed improved attention and reduced defiance/opposition. Read on PubMed
Mensi et al., 2021 – Real-world observational study with 131 ASD children/adolescents confirmed safety and behavioral improvements with PS128. Read on MDPI
Wu et al., 2021 – RCT involving Tourette’s kids revealed ADHD symptom improvements with PS128. Read here
Liao et al., 2021 – Combined PS128 + oxytocin therapy in ASD yielded enhanced social and behavioral metrics. Read study
Additional animal studies show PS128 improves brain neurotransmission and reduces neuroinflammation—pointing to broader gut-brain effects.
I know how exhausting life can feel when raising a neurodivergent child.
But I promise—small things matter:
A day with one fewer meltdown
A better night’s sleep
A calmer morning routine
PS128 gave our family just that: some calm, some focus, some restored hope.
If you and your child could use a little help—embrace this gentle option. Talk to your pediatrician, give it 8 weeks, and track any changes you see.
You’re not alone. I’m here—pushing, hoping, loving alongside you.
Love and sisterhood,
Mom of Mei (and so many small miracles)
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